Giacomo Calzetti, MD
Ophthalmologist and Researcher at the Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland Principal Investigator at the Vista Vision Eye Clinic, Brescia, Italy

Research Approach

Medical retina and inherited retinal diseases


Conducted a natural history study in Usher syndrome type 2A caused by the common c.2299delG mutation
Developed a new method for assessing optic nerve perfusion in patients with Leber's hereditary optic neuropathy
Leading a clinical trial of a new treatment for Leber congenital amaurosis and retinitis pigmentosa


Dr. Calzetti received his medical degree from the University of Parma, Italy in 2010. He then completed residency training in ophthalmology at the University of Parma. He followed this with a postdoctoral research fellowship at the Center for Hereditary Retinal Degenerations at the Scheie Eye Institute, University of Pennsylvania, USA.
Dr. Calzetti is a leading expert in medical retina and inherited retinal diseases. His research focuses on the development of new treatments for these diseases, including gene therapy and gene editing. He has published numerous papers in peer-reviewed journals and has given numerous presentations at international conferences.
Dr. Calzetti participates as site Principal Investigator in an international consortium of inherited retinal disease specialists established to find treatments and cures for blinding retinal diseases, including retinitis pigmentosa, macular degeneration, and Usher syndrome.
Dr. Calzetti is passionate about finding new treatments for patients with inherited retinal diseases. He is committed to improving the lives of these patients and preserving their vision.